منابع مشابه
Human-animal Chimeras: Human Dignity, Moral Status, and Species Prejudice
The creation of chimeras by introducing human stem cells into nonhuman animals has provoked intense concerns. Addressing objections that appeal to human dignity, I focus in this essay on stem cell research intended to generate human neurons in Great Apes and rodents. After considering samples of dignitybased objections from the literature, I examine the underlying assumption that nonhuman anima...
متن کاملExtending healthy life span--from yeast to humans.
When the food intake of organisms such as yeast and rodents is reduced (dietary restriction), they live longer than organisms fed a normal diet. A similar effect is seen when the activity of nutrient-sensing pathways is reduced by mutations or chemical inhibitors. In rodents, both dietary restriction and decreased nutrient-sensing pathway activity can lower the incidence of age-related loss of ...
متن کاملBrain weight and life-span in primate species.
In haplorhine primates (tarsiers, monkeys, apes, and humans), there is a significant correlation between brain weight and maximum life-span when the effect of body size is removed. There is also a significant correlation in haplorhine primates between brain weight and female age at first reproduction. For strepsirhine primates (lorises and lemurs), there are no significant correlations between ...
متن کاملBrain structures and life-span in primate species.
In haplorhine primates, when the effect of body weight is removed, brain weight is correlated with maximum recorded life-span. In this paper we have analyzed the relationships between volumes of specific brain structures and life-span. When the effect of body weight is removed, the volumes of many brain structures are significantly, positively correlated with maximum recorded life-span. However...
متن کاملMouse-chick neural chimeras.
Embryonic chimera production was used to study the developmental processes of the mouse nervous system. The difficulty of performing in situ transplantation experiments of neural primordium of mouse embryo was overcome by isotopic and isochronic grafting of mouse neural tube fragments into chick embryo. Mouse neural tube cells differentiated perfectly in ovo and neural crest cells associated wi...
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ژورنال
عنوان ژورنال: Nature Reports Stem Cells
سال: 2007
ISSN: 1754-8705
DOI: 10.1038/stemcells.2007.111